Silencing of OIP5-AS1 Protects Endothelial Cells From ox-LDL-Triggered Injury by Regulating KLF5 Expression via Sponging miR-135a-5p

Silencing of OIP5-AS1 Protects Endothelial Cells From ox-LDL-Triggered Injury by Regulating KLF5 Expression via Sponging miR-135a-5p

Background: Long non-coding RNAs (lncRNAs) have been implicated in the pathogenesis of atherosclerosis. LncRNA OIP5 antisense RNA 1 (OIP5-AS1) has been found to be associated with the development of atherosclerosis. In this study, we further investigated the molecular basis of OIP5-AS1 in atheroscle...

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Bibliographic Details
Main Authors: Minghu Zhao, Yuanyuan Yang, Jingchao Li, Min Lu, Yu Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
AS
OIP5-AS1
miR-135a-5p
KLF5
ox-LDL
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.596506/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.596506/full

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