Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA

Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing the COVID-19 respiratory disease pandemic utilizes unique 2′-<span style="font-variant: small-caps;">O</span>-methyltransferase (2′-O-MTase) capping machinery to camouflage its RNA from innate immune recog...

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Bibliographic Details
Main Authors: José Antonio Encinar, Javier A. Menendez
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Viruses
Subjects:
COVID-19
drug repurposing
methylation
methyltransferases
computational screening
molecular docking
Online Access:https://www.mdpi.com/1999-4915/12/5/525

Internet

https://www.mdpi.com/1999-4915/12/5/525

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