Age-Related Gene Alteration in Naïve and Memory T cells Using Precise Age-Tracking Model

Age-Related Gene Alteration in Naïve and Memory T cells Using Precise Age-Tracking Model

In aged individuals, age-related changes in immune cells, especially T cell deficiency, are associated with an increased incidence of infection, tumor, and autoimmune disease, as well as an impaired response to vaccination. However, the features of gene expression levels in aged T cells are still un...

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Bibliographic Details
Main Authors: Xiaofeng Yang, Xin Wang, Lei Lei, Lina Sun, Anjun Jiao, Kun Zhu, Tao Xie, Haiyan Liu, Xingzhe Zhang, Yanhong Su, Cangang Zhang, Lin Shi, Dan Zhang, Huiqiang Zheng, Jiahui Zhang, Xiaobin Liu, Xiaobo Zhou, Chenming Sun, Baojun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
aged T cells
naïve T cells
TCRδCreERR26ZsGreen mice
CD4 T cells
CD8 T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.624380/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.624380/full

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