A unifying mechanism for cancer cell death through ion channel activation by HAMLET.

A unifying mechanism for cancer cell death through ion channel activation by HAMLET.

Ion channels and ion fluxes control many aspects of tissue homeostasis. During oncogenic transformation, critical ion channel functions may be perturbed but conserved tumor specific ion fluxes remain to be defined. Here we used the tumoricidal protein-lipid complex HAMLET as a probe to identify ion...

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Bibliographic Details
Main Authors: Petter Storm, Thomas Kjaer Klausen, Maria Trulsson, James Ho C S, Marion Dosnon, Tomas Westergren, Yinxia Chao, Anna Rydström, Henry Yang, Stine Falsig Pedersen, Catharina Svanborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23505537/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23505537/?tool=EBI

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