In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging

In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging

Follicular helper CD4 T (Tfh) cells play an essential role in the formation of germinal centers (GCs), where mature B cells proliferate, differentiate, and provide long-term protective humoral responses. Despite the extensive phenotypic characterization and identification of human Tfh cell subsets,...

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Bibliographic Details
Main Authors: Kalliopi Ioannidou, Daba-Rokhya Ndiaye, Alessandra Noto, Craig Fenwick, Sotirios P. Fortis, Giuseppe Pantaleo, Constantinos Petrovas, Laurence de Leval
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
follicular helper T cells
multiplexed imaging
heterogeneity
germinal center
tonsil
angioimmunoblastic T-cell lymphoma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607626/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.607626/full

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