Mycobacterium tuberculosis growth following aerobic expression of the DosR regulon.

The Mycobacterium tuberculosis regulator DosR is induced by multiple stimuli including hypoxia, nitric oxide and redox stress. Overlap of these stimuli with conditions thought to promote latency in infected patients fuels a model in which DosR regulon expression is correlated with bacteriostasis in...

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Bibliographic Details
Main Authors: Kyle Minch, Tige Rustad, David R Sherman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338750?pdf=render