Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

Abstract Background Neurotrophic tropomyosin receptor kinases (NTRKs) are a gene family function as oncogene or tumor suppressor gene in distinct cancers. We aimed to investigate the methylation and expression profiles and prognostic value of NTRKs gene in colorectal cancer (CRC). Methods An analysi...

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Bibliographic Details
Main Authors: Zijian Chen, Zenghong Huang, Yanxin Luo, Qi Zou, Liangliang Bai, Guannan Tang, Xiaolin Wang, Guangwen Cao, Meijin Huang, Jun Xiang, Huichuan Yu
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Translational Medicine
Subjects:
NTRKs
NTRK3
Methylation
Colorectal cancer
Prognosis
Online Access:https://doi.org/10.1186/s12967-021-02740-6

Internet

https://doi.org/10.1186/s12967-021-02740-6

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