Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

Nearly 50% of cancer patients undergo radiotherapy. Late radiotherapy toxicity affects quality-of-life in long-term cancer survivors and risk of side-effects in a minority limits doses prescribed to the majority of patients. Development of a test predicting risk of toxicity could benefit many cancer...

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Bibliographic Details
Main Authors: Sarah L. Kerns, Leila Dorling, Laura Fachal, Søren Bentzen, Paul D.P. Pharoah, Daniel R. Barnes, Antonio Gómez-Caamaño, Ana M. Carballo, David P. Dearnaley, Paula Peleteiro, Sarah L. Gulliford, Emma Hall, Kyriaki Michailidou, Ángel Carracedo, Michael Sia, Richard Stock, Nelson N. Stone, Matthew R. Sydes, Jonathan P. Tyrer, Shahana Ahmed, Matthew Parliament, Harry Ostrer, Barry S. Rosenstein, Ana Vega, Neil G. Burnet, Alison M. Dunning, Gillian C. Barnett, Catharine M.L. West
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:EBioMedicine
Subjects:
Radiogenomics
Genome-wide association study
Prostate cancer
Radiation toxicity
Cancer survivorship
Quality of life
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416303279

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http://www.sciencedirect.com/science/article/pii/S2352396416303279

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