Accumulation of Insoluble α-Synuclein in Dementia with Lewy Bodies
The α-synuclein (αSN) protein is thought to play a central role in the pathogenesis of neurodegenerative diseases where it aggregates to form intracellular inclusions. We have used Western blotting to examine the expression levels and solubility of αSN in brain homogenates from dementia with Lewy bo...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2000-06-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996100902869 |