Mechanisms involved in the beneficial effects of spironolactone after myocardial infarction.

<h4>Introduction</h4>Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1 (TIMP-1...

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Main Authors: Marcos F Minicucci, Priscila P dos Santos, Bruna P M Rafacho, Andrea F Gonçalves, Renata A C Silva, Fernanda Chiuso-Minicucci, Paula S Azevedo, Bertha F Polegato, Katashi Okoshi, Elenize J Pereira, Sergio A R Paiva, Leonardo A M Zornoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24098808/?tool=EBI