Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

Widespread coronavirus disease (COVID)-19 is causing pneumonia, respiratory and multiorgan failure in susceptible individuals. Dysregulated immune response marks severe COVID-19, but the immunological mechanisms driving COVID-19 pathogenesis are still largely unknown, which is hampering the developm...

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Bibliographic Details
Main Authors: Sergej Tomić, Jelena Đokić, Dejan Stevanović, Nataša Ilić, Alisa Gruden-Movsesijan, Miroslav Dinić, Dušan Radojević, Marina Bekić, Nebojša Mitrović, Ratko Tomašević, Dragan Mikić, Dragoš Stojanović, Miodrag Čolić
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
COVID-19
myeloid-derived suppressor cells
autophagy
regulatory lymphocytes
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.614599/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.614599/full

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