Specific Anti-Leukemic Activity of the Peptide Warnericin RK and Analogues and Visualization of Their Effect on Cancer Cells by Chemical Raman Imaging.

Antimicrobial peptides can be used as therapeutic agents against cancer cells. Warnericin RK and derivatives (WarnG20D and WarnF14V) were tested on various, solid tumor or leukemia, cancer cells. These peptides appeared to be cytotoxic on all the cell types tested, cancerous as well healthy, but ver...

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Bibliographic Details
Main Authors: Clémence Loiseau, Jacques Augenstreich, Adrienne Marchand, Etienne Harté, Martine Garcia, Julien Verdon, Marc Mesnil, Sophie Lecomte, Jean-Marc Berjeaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5012605?pdf=render