Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Current concepts suggest that exposure to THC during adolescence may act as a risk factor for the development of psychiatric disorders later in life. However, the molecular underpinnings of this vulnerability are still poorly understood. To analyze this, we investigated whether and how THC exposure...

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Bibliographic Details
Main Authors: Tiziana Rubino, Pamela Prini, Fabiana Piscitelli, Erica Zamberletti, Massimo Trusel, Miriam Melis, Claudia Sagheddu, Alessia Ligresti, Raffaella Tonini, Vincenzo Di Marzo, Daniela Parolaro
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
Endocannabinoid system
Adolescence
Prefrontal cortex
NMDA receptors
AMPA receptors
Spine density
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002873

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http://www.sciencedirect.com/science/article/pii/S0969996114002873

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