DNA Methylation Reprogramming during Mammalian Development

DNA methylation (5-methylcytosine, 5mC) is a major form of DNA modification in the mammalian genome that plays critical roles in chromatin structure and gene expression. In general, DNA methylation is stably maintained in somatic tissues. However, DNA methylation patterns and levels show dynamic cha...

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Bibliographic Details
Main Authors: Yang Zeng, Taiping Chen
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/4/257