Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration

Abstract Background Prostate cancer is the most common malignant tumor of male genitourinary system, molecular mechanism of which is still not clear. PSMC2 (proteasome 26S subunit ATPase 2) is a key member of the 19S regulatory subunit of 26S proteasome, whose relationship with prostate cancer is ra...

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Bibliographic Details
Main Authors: Qingke Chen, Lingmin Fu, Jieping Hu, Guanghua Guo, An Xie
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-01934-8