The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction

The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction

Abstract Background The aim of the present study was to verify whether propofol impaired learning and memory through the interplay of N-methyl-D-aspartate (NMDA) receptor with brain-derived neurotrophic factor (BDNF)-tyrosine kinase B (TrkB) signaling pathway. Methods 120 Sprague-Dawley (SD) rats we...

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Bibliographic Details
Main Authors: Junfei Zhou, Fang Wang, Jun Zhang, Jianfeng Li, Li Ma, Tieli Dong, Zhigang Zhuang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Anesthesiology
Subjects:
NMDA
BDNF
TrkB
Propofol
Cognition dysfunction
Online Access:http://link.springer.com/article/10.1186/s12871-018-0491-y

Internet

http://link.springer.com/article/10.1186/s12871-018-0491-y

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