Xanthine oxidase inhibitors for prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials

Xanthine oxidase inhibitors for prevention of cardiovascular events: a systematic review and meta-analysis of randomized controlled trials

Abstract Background Xanthine oxidase inhibitors (XOI), classified as purine-like (allopurinol and oxypurinol) and non-purine (febuxostat and topiroxostat) XOI, present antioxidant properties by reducing the production of reactive oxygen species derived from purine metabolism. Oxidative stress is an...

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Bibliographic Details
Main Authors: Markus Bredemeier, Lediane Moreira Lopes, Matheus Augusto Eisenreich, Sheila Hickmann, Guilherme Kopik Bongiorno, Rui d’Avila, André Luis Bittencourt Morsch, Fernando da Silva Stein, Guilherme Gomes Dias Campos
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Gout
Treatment
Cardiovascular disease
Meta-analysis
Xanthine Oxidase inhibitors
Online Access:http://link.springer.com/article/10.1186/s12872-018-0757-9

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http://link.springer.com/article/10.1186/s12872-018-0757-9

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