Cellular Levels of Oxidative Stress Affect the Response of Cervical Cancer Cells to Chemotherapeutic Agents

Treatment of advanced and relapsed cervical cancer is frequently ineffective, due in large part to chemoresistance. To examine the pathways responsible, we employed the cervical carcinoma-derived SiHa and CaSki cells as cellular models of resistance and sensitivity, respectively, to treatment with c...

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Bibliographic Details
Main Authors: Maria Filippova, Valery Filippov, Vonetta M. Williams, Kangling Zhang, Anatolii Kokoza, Svetlana Bashkirova, Penelope Duerksen-Hughes
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/574659