The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity

The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity

Obesity and high fat diet consumption contribute to the development of metabolic disorders, insulin resistance, neuroinflammation, and cognitive impairments. CNS administration of insulin into the brain can attenuate these cognitive impairments. The present study investigated whether hippocampal-dep...

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Bibliographic Details
Main Authors: Joanne M. Gladding, Kirsten N. Abbott, Christopher P. Antoniadis, Angela Stuart, Denovan P. Begg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Endocrinology
Subjects:
insulin
hippocampus
spatial cognition
high fat diet
diet induced obesity
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00752/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00752/full

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