Functional Analyses of RUNX3 and CaMKIINα in Ovarian Cancer Cell Lines Reveal Tumor-Suppressive Functions for CaMKIINα and Dichotomous Roles for RUNX3 Transcript Variants

Functional Analyses of RUNX3 and CaMKIINα in Ovarian Cancer Cell Lines Reveal Tumor-Suppressive Functions for CaMKIINα and Dichotomous Roles for RUNX3 Transcript Variants

(1) Background: Epithelial ovarian cancer (EOC) is the most lethal cancer of the female reproductive system. In an earlier study, we identified multiple genes as hypermethylated in tumors of patients with poor prognosis. The most promising combination of markers to predict a patient’s outcome was Ca...

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Bibliographic Details
Main Authors: Karolin Heinze, Daniel Kritsch, Alexander S. Mosig, Matthias Dürst, Norman Häfner, Ingo B. Runnebaum
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
epithelial ovarian cancer
platin resistance
RUNX3
CaMKIINα
tumor suppressor
Online Access:http://www.mdpi.com/1422-0067/19/1/253

Internet

http://www.mdpi.com/1422-0067/19/1/253

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