Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma.

BACKGROUND:Esophageal cancer remains one of the hardest cancers to treat with rising incidence rates, low overall survival and high levels of treatment resistance. The lack of clinically available biomarkers hinder diagnosis and treatment stratification. While large scale sequencing approaches have...

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Bibliographic Details
Main Authors: Ines Lohse, Hassan Al-Ali, Claude-Henry Volmar, Annamil D Alvarez Trotta, Shaun P Brothers, Anthony J Capobianco, Claes Wahlestedt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6136712?pdf=render