Discovery and Validation of a Three-Cytokine Plasma Signature as a Biomarker for Diagnosis of Pediatric Tuberculosis

Discovery and Validation of a Three-Cytokine Plasma Signature as a Biomarker for Diagnosis of Pediatric Tuberculosis

Pediatric TB poses challenge in diagnosis due to the paucibacillary nature of the disease. We conducted a prospective diagnostic study to identify immune biomarkers of pediatric TB and controls (discovery cohort) and obtained a separate “validation” cohort of confirmed cases of pediatric TB and cont...

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Bibliographic Details
Main Authors: Nathella Pavan Kumar, Syed Hissar, Kannan Thiruvengadam, Velayuthum V. Banurekha, N. Suresh, Janani Shankar, Elilarasi S, Gomathi N S, Kalpana S, Ganesh J, Aravind M A, Dhanaraj Baskaran, Srikanth Tripathy, Soumya Swaminathan, Subash Babu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
pediatric tuberculosis
cytokines
biomarkers
ELISA
tuberculosis diagnostics
anti-tuberculosis treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.653898/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.653898/full

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