Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas

Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas

Diffuse Midline Gliomas with Histone 3-Lysine-27-Methionine (H3K27M) mutation constitute the majority of Diffuse Intrinsic Pontine Glioma (DIPG), which is the most aggressive form of pediatric glioma with a dire prognosis. DIPG are lethal tumors found in younger children with a median survival &...

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Bibliographic Details
Main Authors: John P. Welby, Tatiana Kaptzan, Anton Wohl, Timothy E. Peterson, Aditya Raghunathan, Desmond A. Brown, Shiv K. Gupta, Liang Zhang, David J. Daniels
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Oncology
Subjects:
glioma
DIPG
diffuse intrinsic pontine glioma
H3K27M
xenograft
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00092/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00092/full

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