Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis

Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis

Summary: As an important regulator of macrophage cholesterol efflux and HDL biogenesis, miR-33 is a promising target for treatment of atherosclerosis, and numerous studies demonstrate that inhibition of miR-33 increases HDL levels and reduces plaque burden. However, important questions remain about...

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Bibliographic Details
Main Authors: Nathan L. Price, Noemi Rotllan, Alberto Canfrán-Duque, Xinbo Zhang, Paramita Pati, Noemi Arias, Jack Moen, Manuel Mayr, David A. Ford, Ángel Baldán, Yajaira Suárez, Carlos Fernández-Hernando
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717314559

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http://www.sciencedirect.com/science/article/pii/S2211124717314559

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