A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

<p>Abstract</p> <p>Background</p> <p>All archaeal and many bacterial genomes contain Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) and variable arrays of the CRISPR-associated (<it>cas</it>) genes that have been previously implicated in a...

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Bibliographic Details
Main Authors: Wolf Yuri I, Shabalina Svetlana A, Grishin Nick V, Makarova Kira S, Koonin Eugene V
Format: Article
Language:English
Published: BMC 2006-03-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/1/1/7

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http://www.biology-direct.com/content/1/1/7

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