Identification of Serum MicroRNAs as Novel Biomarkers in Esophageal Squamous Cell Carcinoma Using Feature Selection Algorithms

Identification of Serum MicroRNAs as Novel Biomarkers in Esophageal Squamous Cell Carcinoma Using Feature Selection Algorithms

Introduction: Circulating microRNAs (miRNAs) are promising molecular biomarkers for the early detection of esophageal squamous cell carcinoma (ESCC). We investigated the serum miRNA expression profiles from microarray-based technologies and evaluated the diagnostic value of serum miRNAs as potential...

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Bibliographic Details
Main Authors: Deqiang Zheng, Yuanjie Ding, Qing Ma, Lei Zhao, Xudong Guo, Yi Shen, Yan He, Wenqiang Wei, Fen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
serum microRNA
multiple-testing criterion
Lasso logistic regression
penalized support vector machine
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00674/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00674/full

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