Amphotericin B and Other Polyenes—Discovery, Clinical Use, Mode of Action and Drug Resistance

Although polyenes were the first broad spectrum antifungal drugs on the market, after 70 years they are still the gold standard to treat a variety of fungal infections. Polyenes such as amphotericin B have a controversial image. They are the antifungal drug class with the broadest spectrum, resistan...

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Bibliographic Details
Main Authors: Hans Carolus, Siebe Pierson, Katrien Lagrou, Patrick Van Dijck
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/6/4/321