1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.

Immune escape and metastasis are the hallmarks of several types of cancer including bladder cancer. One of the mechanisms involved in these processes has been linked to indoleamine 2,3-dioxygenase (IDO). Although IDO is classically recognized for its immunomodulatory property, it has presented nonim...

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Main Authors: Rodrigo Barbosa Oliveira Brito, Camila Soares Malta, Diego Mota Souza, Luiz Henrique Gomes Matheus, Yves Silva Teles Matos, Chrisna Souza Silva, Janaína Mendes Ferreira, Valeria Sutti Nunes, Cristiane Miranda França, Humberto Dellê
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0134858