Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via Biginelli reaction promoted by bismuth(III)nitrate or PPh3 without solvent

Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones via Biginelli reaction promoted by bismuth(III)nitrate or PPh3 without solvent

3,4-Dihydropyrimidinones/thiones and their derivatives are synthesized via Biginelli routes involving an aldehyde, 1,3-dicarbonyl compound and urea or thiourea. Use of catalysts such as bismuth nitrate in acetonitrile or PPh3 without solvent lead to higher yields compared to the classic method using...

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Bibliographic Details
Main Authors: Hela Slimi, Younes Moussaoui, Ridha ben Salem
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Arabian Journal of Chemistry
Subjects:
Biginelli reaction
3,4-Dihydropyrimidinones
Solvent free conditions
Bismuth(III) nitrate
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535211001626

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http://www.sciencedirect.com/science/article/pii/S1878535211001626

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