Blocking Extracellular Chaperones to Improve Cardiac Regeneration

Chronic or acute insults to the myocardium are responsible for the onset of cardiomyopathy and heart failure. Due to the poor regenerative ability of the human adult heart, the survival of cardiomyocytes is a prerequisite to support heart function. Chaperone proteins, by regulating sarcomeric protei...

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Bibliographic Details
Main Authors: Laura Seclì, Matteo Sorge, Alessandro Morotti, Mara Brancaccio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00411/full