New Peptide-Conjugated Chlorin-Type Photosensitizer Targeting Neuropilin-1 for Anti-Vascular Targeted Photodynamic Therapy

New Peptide-Conjugated Chlorin-Type Photosensitizer Targeting Neuropilin-1 for Anti-Vascular Targeted Photodynamic Therapy

Photodynamic therapy (PDT) is a cancer treatment modality that requires three components, namely light, dioxygen and a photosensitizing agent. After light excitation, the photosensitizer (PS) in its excited state transfers its energy to oxygen, which leads to photooxidation reactions. In order to im...

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Bibliographic Details
Main Authors: Ezatul Ezleen Kamarulzaman, Amirah Mohd Gazzali, Samir Acherar, Céline Frochot, Muriel Barberi-Heyob, Cédric Boura, Patrick Chaimbault, Estelle Sibille, Habibah A. Wahab, Régis Vanderesse
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
photodynamic therapy
peptide targeted photosensitizer
neuropilin-1
in vivo stability
Online Access:http://www.mdpi.com/1422-0067/16/10/24059

Internet

http://www.mdpi.com/1422-0067/16/10/24059

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