Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation.

Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental progeroid disorder commonly caused by a point mutation in the LMNA gene that results in the increased activation of an intra-exonic splice site and the production of a truncated lamin A protein, named progerin. In our previous work, ind...

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Bibliographic Details
Main Authors: Agustín Sola Carvajal, Tomás McKenna, Emelie Wallén Arzt, Maria Eriksson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4459694?pdf=render