Serum 8,12-iso-iPF2α-VI isoprostane marker of oxidative damage and cognition deficits in children with konzo.

We sought to determine whether motor and cognitive deficits associated with cassava (food) cyanogenic poisoning were associated with high concentrations of F2-isoprostanes, well-established indicators of oxidative damage. Concentrations of serum F2-isoprostanes were quantified by LC-MS/MS and anchor...

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Main Authors: Bumoko G Makila-Mabe, Kambale J Kikandau, Thérèse M Sombo, Daniel L Okitundu, Jean-Claude Mwanza, Michael J Boivin, Mumba D Ngoyi, Jean-Jacques T Muyembe, Jean-Pierre Banea, Gerard R Boss, Desiré Tshala-Katumbay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107191