A Novel Synthetic Approach to C-Glycosyl-D- and L-Alanines

A Novel Synthetic Approach to C-Glycosyl-D- and L-Alanines

C-Glycosyl-(S)- and (R)-alanines 12a and 12b were synthesized from the known β-C-glycoside 1. The nitrogen function was introduced by aza-Claisen rearrangement of the allylic thiocyanate 7, derived from the corresponding alcohol 6. The absolute configuration of the newly created chiral carbon cen...

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Bibliographic Details
Main Authors: Miroslava Martinková, Jozef Gonda, Jozef Kožíšek, Jana Raschmanová, Alexandra Novodomská, Lucia Perasinová
Format: Article
Language:English
Published: MDPI AG 2008-12-01
Series:Molecules
Subjects:
C-Glycosyl amino acids
C-Glycosyl alanine
[3
3]-Sigmatropic rearrangements
Microwave irradiation
X-ray diffraction
Online Access:http://www.mdpi.com/1420-3049/13/12/3171/

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http://www.mdpi.com/1420-3049/13/12/3171/

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