rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

Ana Rey-Rico,1 Jagadeesh K Venkatesan,1 Gertrud Schmitt,1 Angel Concheiro,2 Henning Madry,1,3 Carmen Alvarez-Lorenzo,2 Magali Cucchiarini1 1Center of Experimental Orthopedics, Saarland University Medical Center, Homburg, Germany; 2Department of Pharmacology, Pharmacy and Pharmaceutical Technology,...

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Bibliographic Details
Main Authors: Rey-Rico A, Venkatesan JK, Schmitt G, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M
Format: Article
Language:English
Published: Dove Medical Press 2017-09-01
Series:International Journal of Nanomedicine
Subjects:
human articular cartilage
rAAV gene transfer
TGF-
poloxamer
poloxamine.
Online Access:https://www.dovepress.com/raav-mediated-overexpression-of-tgf-beta-via-vector-delivery-in-polyme-peer-reviewed-article-IJN

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https://www.dovepress.com/raav-mediated-overexpression-of-tgf-beta-via-vector-delivery-in-polyme-peer-reviewed-article-IJN

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