How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?

How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells?

Conserved dopamine neurotrophic factor protects and rescues dopaminergic neurodegeneration induced by 6-hydroxydopamine in vivo, but its potential value in treating Parkinson's disease remains controversial. Here, we used the proteasome inhibitors lactacystin and MG132 to induce neurodegenerati...

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Bibliographic Details
Main Authors: Jia-ming Mei, Chao-shi Niu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; conserved dopamine neurotrophic factor; Parkinson′s disease; proteasomal inhibitor; 26S proteasome; alpha-synuclein; lactacystin; MG-132; glutamyl peptide hydrolase; chymotrypsin; trypsin; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=7;spage=1145;epage=1151;aulast=Mei

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=7;spage=1145;epage=1151;aulast=Mei

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