Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia.

Trauma/hemorrhagic shock is a complex physiological phenomenon that leads to dysregulation of many molecular pathways. For over a decade, hypertonic saline (HTS) has been used as an alternative resuscitation fluid in the setting of trauma/hemorrhagic shock. In addition to restoring circulating volum...

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Bibliographic Details
Main Authors: Sanchayita Mitra, Daran Schiller, Cameron Anderson, Fabia Gamboni, Angelo D'Alessandro, Margeurite Kelher, Christopher C Silliman, Anirban Banerjee, Kenneth L Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5734749?pdf=render