Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.

Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway.

<h4>Background</h4>PTEN (phosphatase and tensin homologue deleted on chromosome ten) is a tumor suppressor gene implicated in a wide variety of human cancers, including glioblastoma. PTEN is a major negative regulator of the PI3K/Akt signaling pathway. Most human gliomas show high levels...

Full description

Bibliographic Details
Main Authors: Venkata Ramesh Dasari, Kiranpreet Kaur, Kiran Kumar Velpula, Meena Gujrati, Daniel Fassett, Jeffrey D Klopfenstein, Dzung H Dinh, Jasti S Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20436671/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20436671/?tool=EBI

Similar Items