Simulated microgravity induces nuclear translocation of Bax and BCL-2 in glial cultured C6 cells

Alterations in the control of apoptotic processes were observed in cells during space flight or under simulated microgravity, the latter obtained with the 3D-Random Positioning Machine (3D-RPM).Usually the proteins Bax and Bcl-2, act as pro- or anti-apoptotic regulators. Here we investigated the eff...

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Bibliographic Details
Main Authors: Tommaso Bonfiglio, Federico Biggi, Anna Maria Bassi, Sara Ferrando, Lorenzo Gallus, Fabrizio Loiacono, Silvia Ravera, Marino Rottigni, Sonia Scarfì, Felice Strollo, Stefania Vernazza, Maurizio Sabbatini, Maria A. Masini
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401836290X