Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559

Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559

<p>Abstract</p> <p>Background</p> <p>TC-2559 is a selective α4β2 subtype of nicotinic acetylcholine receptor (nAChR) partial agonist and α4β2 nAChR activation has been related to antinociception. The aim of this study is to investigate the analgesic effect of TC-2559 an...

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Bibliographic Details
Main Authors: Peng Li-Chao, Huang Lan-Ting, Fan Jing, Han Lei, Cheng Long-Zhen, Wang Yun
Format: Article
Language:English
Published: SAGE Publishing 2011-08-01
Series:Molecular Pain
Subjects:
TC-2559
α4β2 nAChRs
Formalin test
CCI
sIPSCs
Pain
Spinal cord slice
Online Access:http://www.molecularpain.com/content/7/1/56

Internet

http://www.molecularpain.com/content/7/1/56

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