Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells

Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells

Abstract Background Tuberculosis (TB) is one of the most common infectious diseases worldwide. During active tuberculosis, T helper (Th) 17 cells are decreased, however the association with inhibitory immune regulation is unclear. Methods We enrolled 27 patients with TB and 20 age- and sex-matched c...

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Bibliographic Details
Main Authors: Chin-Chung Shu, Ming-Fang Wu, Jann-Yuan Wang, Hsin-Chih Lai, Li-Na Lee, Bor-Luen Chiang, Chong-Jen Yu
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Respiratory Research
Subjects:
Programmed cell death 1
Cytotoxic T-lymphocyte-associated protein 4
Tuberculosis
Th17 cells
Regulatory T cells
Th2 cells
Online Access:http://link.springer.com/article/10.1186/s12931-017-0580-3

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http://link.springer.com/article/10.1186/s12931-017-0580-3

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