Treatment Intensification in HIV-Infected Patients Is Associated With Reduced Frequencies of Regulatory T Cells

Treatment Intensification in HIV-Infected Patients Is Associated With Reduced Frequencies of Regulatory T Cells

In untreated HIV infection, the efficacy of T cell responses decreases over the disease course, resulting in disease progression. The reasons for this development are not completely understood. However, immunosuppressive cells are supposedly crucially involved. Treatment strategies to avoid the indu...

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Bibliographic Details
Main Authors: Eva M. Grützner, Tanja Hoffmann, Eva Wolf, Elke Gersbacher, Ashley Neizert, Renate Stirner, Ramona Pauli, Albrecht Ulmer, Jürgen Brust, Johannes R. Bogner, Hans Jaeger, Rika Draenert
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
HIV-1
treatment intensification
immune suppressive cells
myeloid-derived suppressor cells
regulatory T cells
regulatory B cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00811/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00811/full

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