From Bench to Bedside: Targeting Epigenetics for Cancer Therapy

The initiation and progression of cancer not only involves genetic abnormalities, but also epigenetic alterations, such as DNA methylation and histone modifications. Epigenetics refers to the heritable changes that do not involve any structural changes in the target gene, i.e., DNA sequence and prot...

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Bibliographic Details
Main Authors: Jin-xu Fang, Gui-deng Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2011-12-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/27