Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Tauopathies are a class of neurodegenerative diseases, including Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy, which are associated with the pathological aggregation of tau protein into neurofibrillary tangles (NFT). Studies have characterized tau as a “prion-...

Full description

Bibliographic Details
Main Authors: Patrick Reilly, Charisse N. Winston, Kelsey R. Baron, Margarita Trejo, Edward M. Rockenstein, Johnny C. Akers, Najla Kfoury, Marc Diamond, Eliezer Masliah, Robert A. Rissman, Shauna H. Yuan
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Neurobiology of Disease
Subjects:
Tau
Neurofibrillary tangles
Induced pluripotent stem cells
Exosomes
Propagation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301316

Internet

http://www.sciencedirect.com/science/article/pii/S0969996117301316

Similar Items