Raloxifene Ameliorates Glucosamine-Induced Insulin Resistance in Ovariectomized Rats

Raloxifene Ameliorates Glucosamine-Induced Insulin Resistance in Ovariectomized Rats

Osteoarthritis (OA) and osteoporosis (OP) are common among older women, especially postmenopausal women. Glucosamine (GlcN) is a common medication for OA, but it may induce insulin resistance and β-cell dysfunction, especially if ovarian hormones are lacking. Raloxifene (RLX) is a selective estrogen...

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Bibliographic Details
Main Authors: Chung-Hwan Chen, Tsung-Lin Cheng, Chi-Fen Chang, Hsuan-Ti Huang, Sung-Yen Lin, Meng-Hsing Wu, Lin Kang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
apoptosis
endoplasmic reticulum stress
glucosamine
pancreatic β-cell dysfunction
ovariectomy
raloxifene
Online Access:https://www.mdpi.com/2227-9059/9/9/1114

Internet

https://www.mdpi.com/2227-9059/9/9/1114

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