Plant-made trastuzumab (herceptin) inhibits HER2/Neu+ cell proliferation and retards tumor growth.

BACKGROUND: Plant biotechnology provides a valuable contribution to global health, in part because it can decrease the cost of pharmaceutical products. Breast cancer can now be successfully treated by a humanized monoclonal antibody (mAb), trastuzumab (Herceptin). A course of treatment, however, is...

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Bibliographic Details
Main Authors: Tatiana V Komarova, Vyacheslav S Kosorukov, Olga Y Frolova, Igor V Petrunia, Ksenia A Skrypnik, Yuri Y Gleba, Yuri L Dorokhov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3048398?pdf=render