Seizures are a druggable mechanistic link between TBI and subsequent tauopathy

Seizures are a druggable mechanistic link between TBI and subsequent tauopathy

Traumatic brain injury (TBI) is a prominent risk factor for dementias including tauopathies like chronic traumatic encephalopathy (CTE). The mechanisms that promote prion-like spreading of Tau aggregates after TBI are not fully understood, in part due to lack of tractable animal models. Here, we tes...

Full description

Bibliographic Details
Main Authors: Hadeel Alyenbaawi, Richard Kanyo, Laszlo F Locskai, Razieh Kamali-Jamil, Michèle G DuVal, Qing Bai, Holger Wille, Edward A Burton, W Ted Allison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
traumatic brain injury
tauopathy
post-traumatic seizures
epilepsy
anti-epileptics
neurotrauma
Online Access:https://elifesciences.org/articles/58744

Internet

https://elifesciences.org/articles/58744

Similar Items