Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells

Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Current chemotherapy regimens include a combination of 5-fluorouracil (5-FU) and cisplatin, but more efficient therapy strategies are needed to increase 5-year survival. Alterations in the signaling pathway of the tu...

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Bibliographic Details
Main Authors: Rossana C. Soletti, Deborah Biasoli, Nathassya A.L.V. Rodrigues, João M.A. Delou, Renata Maciel, Vera L.A. Chagas, Rodrigo A.P. Martins, Stevens K. Rehen, Helena L. Borges
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317302024