Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures

Macrophages are mononuclear phagocytes that constitute a first line of defense against pathogens. While lethal to many microbes, they are the primary host cells of Leishmania spp. parasites, the obligate intracellular pathogens that cause leishmaniasis. We conducted transcriptomic profiling of two L...

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Bibliographic Details
Main Authors: Maria Cecilia Fernandes, Laura A. L. Dillon, Ashton Trey Belew, Hector Corrada Bravo, David M. Mosser, Najib M. El-Sayed
Format: Article
Language:English
Published: American Society for Microbiology 2016-05-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/3/e00027-16