Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures
Macrophages are mononuclear phagocytes that constitute a first line of defense against pathogens. While lethal to many microbes, they are the primary host cells of Leishmania spp. parasites, the obligate intracellular pathogens that cause leishmaniasis. We conducted transcriptomic profiling of two L...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-05-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/3/e00027-16 |