Analysis of Genomic DNA Methylation Levels in Human Placenta using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

Analysis of Genomic DNA Methylation Levels in Human Placenta using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

Background: DNA-methylation is a common epigenetic tool which plays a crucial role in gene regulation and is essential for cell differentiation and embryonic development. The placenta is an important organ where gene activity can be regulated by epigenetic DNA modifications, including DNA methylatio...

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Bibliographic Details
Main Authors: Sulistyo Emantoko Dwi Putra, Corinna Neuber, Christoph Reichetzeder, Berthold Hocher, Burkhard Kleuser
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Pregnancy
Placenta
Methylation
Global
LC-MS/MS
Fetal programming
Clinical
Online Access:http://www.karger.com/Article/FullText/358666

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http://www.karger.com/Article/FullText/358666

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